Localisation of a gene causing endocrine neoplasia to a 4 cM region on chromosome 1p35-p36.

  title={Localisation of a gene causing endocrine neoplasia to a 4 cM region on chromosome 1p35-p36.},
  author={Christine Williamson and Anna A. J. Pannett and Joanna T. Pang and Carol Wooding and Mary Ann McCarthy and Mary Noelle Sheppard and J. C. Monson and Richard N. Clayton and Rajesh V Thakker},
  journal={Journal of medical genetics},
  volume={34 8},
The development of some endocrine tumours, such as medullary thyroid carcinomas, phaeochromocytomas, anterior pituitary adenomas, and parathyroid adenomas involve a putative tumour suppressor gene located on chromosome 1p32-pter, a region that represents 111 cM. In order to refine the location of this gene, 93 endocrine tumours (39 parathyroid adenomas, 40 anterior pituitary adenomas, seven pancreatic islet cell adenomas, and seven carcinoids) were investigated for loss of tumour heterozygosity… CONTINUE READING


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Genetic mapping studies of 40 loci and 23 cosmids in chromosome Ipi 3 - 1 1 q 13 , and exclusion of 1 s - calpain as the multiple neoplasia type I gene

  • JT Pang, SE Lloyd, C Wooding
  • Hum Genet
  • 1996

Report and abstracts of the First International Workshop of Human L T Chromosome 1 Mapping 1994 , Bethesda , Maryland , 25 - 27 March 1994

  • NC Dracopoli, GA Bruns, GM Brodeur
  • Cytogenet Cell Genet
  • 1994

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