Local vascular changes induced by the cocarcinogen, phorbol myristate acetate.

@article{Janoff1970LocalVC,
  title={Local vascular changes induced by the cocarcinogen, phorbol myristate acetate.},
  author={Aaron Janoff and Ann C Klassen and Walter Troll},
  journal={Cancer research},
  year={1970},
  volume={30 10},
  pages={2568-71}
}
SUMMARY One ,ig of phorbol myristate acetate, an active tumor promoting agent from croton oil, produces a severe, local vascular reaction in skin (ear) of CF1 and STS mice. The response is characterized by hyperemia and edema formation which can be quantitatively monitored by measuring uptake of circulating ‘251-labeled bovine serum albumin. Micro scopic… CONTINUE READING