Local sleep and learning
@article{Huber2004LocalSA, title={Local sleep and learning}, author={Reto Huber and Maria Felice Ghilardi and Marcello Massimini and Giulio Tononi}, journal={Nature}, year={2004}, volume={430}, pages={78-81} }
Human sleep is a global state whose functions remain unclear. During much of sleep, cortical neurons undergo slow oscillations in membrane potential, which appear in electroencephalograms as slow wave activity (SWA) of <4 Hz. The amount of SWA is homeostatically regulated, increasing after wakefulness and returning to baseline during sleep. It has been suggested that SWA homeostasis may reflect synaptic changes underlying a cellular need for sleep. If this were so, inducing local synaptic…
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Sleep Locally, Act Globally
- Psychology, BiologyThe Neuroscientist : a review journal bringing neurobiology, neurology and psychiatry
- 2012
It is suggested that in animals with brains composed of heavily interconnected and functionally interdependent units, a global regulator of sleep maintains the behavioral shutdown that defines sleep and thereby ensures that local use-dependent functions are performed in a safe and efficient manner.
Sleep orchestrates indices of local plasticity and global network stability in the human cortex
- Biology, PsychologySleep
- 2019
Electrophysiological, behavioral, and molecular indices are used to noninvasively study cortical plasticity and network stability in humans and are consistent with the notion that sleep-specific brain activity patterns reduce the plasticity-stability dilemma by orchestrating local Plasticity and global stability of neural assemblies in the human cortex.
Electrophysiological correlates of sleep homeostasis in freely behaving rats.
- Biology, PsychologyProgress in brain research
- 2011
Sleep homeostasis and cortical synchronization: I. Modeling the effects of synaptic strength on sleep slow waves.
- BiologySleep
- 2007
Experimental results from rat cortical depth recordings and human high-density EEG show similar changes in slow-wave parameters with decreasing SWA, suggesting that the underlying mechanism may indeed be a net decrease in synaptic strength.
Sleep function: current questions and new approaches
- Biology, PsychologyThe European journal of neuroscience
- 2009
Wake experience‐induced local network changes may be sensed by the sleep homeostatic process and used to mediate sleep‐dependent events, benefiting network stabilization and memory consolidation.
Local sleep homeostasis in the avian brain: convergence of sleep function in mammals and birds?
- Biology, PsychologyProceedings of the Royal Society B: Biological Sciences
- 2011
After staying awake watching David Attenborough's The Life of Birds with only one eye, SWA and the slope of slow waves increased only in the hyperpallium—a primary visual processing region—neurologically connected to the stimulated eye, providing the first electrophysiological evidence for local sleep homeostasis in the avian brain.
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