• DOI:10.1038/nature02663
Corpus ID: 4328616

Local sleep and learning

@article{Huber2004LocalSA,
  title={Local sleep and learning},
  author={R. Huber and M. Ghilardi and M. Massimini and G. Tononi},
  journal={Nature},
  year={2004},
  volume={430},
  pages={78-81}
}

• R. Huber, M. Ghilardi, +1 author G. Tononi
• Published 2004
• Biology, Medicine
• Nature

Human sleep is a global state whose functions remain unclear. During much of sleep, cortical neurons undergo slow oscillations in membrane potential, which appear in electroencephalograms as slow wave activity (SWA) of <4 Hz. The amount of SWA is homeostatically regulated, increasing after wakefulness and returning to baseline during sleep. It has been suggested that SWA homeostasis may reflect synaptic changes underlying a cellular need for sleep. If this were so, inducing local synaptic… Expand