Local production and localization of transforming growth factor-beta in tuberculous pleurisy.

@article{Maeda1993LocalPA,
  title={Local production and localization of transforming growth factor-beta in tuberculous pleurisy.},
  author={Juichiro Maeda and Noboru Ueki and Toshihisa Ohkawa and Naomi Iwahashi and Takashi Nakano and Toshikazu Hada and Kazuya Higashino},
  journal={Clinical and experimental immunology},
  year={1993},
  volume={92 1},
  pages={32-8}
}
Transforming growth factor-beta (TGF-beta) is one of the cytokines which play an immunosuppressive role in an inflammatory process. To investigate the local production of TGF-beta, we evaluated the levels of TGF-beta in tuberculous pleural effusions (TBPE) and non-tuberculous benign pleural effusions (non-TBPE) by the growth inhibition assay with Mv1Lu mink lung epithelial cells. The mean level of TGF-beta in TBPE (46.1 +/- 31.5 pM; mean +/- s.d.) was higher than in non-TBPE (21.7 +/- 12.3 pM… CONTINUE READING