Local intramural delivery of L-arginine enhances nitric oxide generation and inhibits lesion formation after balloon angioplasty.

@article{Schwarzacher1997LocalID,
  title={Local intramural delivery of L-arginine enhances nitric oxide generation and inhibits lesion formation after balloon angioplasty.},
  author={Severin Paul Schwarzacher and Tony Kiat Hon Lim and Bing-yin Wang and Robert S. Kernoff and Prim. Univ.-Prof. Dr. Dr. J. Niebauer and John P Cooke and Alan Yeung},
  journal={Circulation},
  year={1997},
  volume={95 7},
  pages={
          1863-9
        }
}
BACKGROUND Long-term oral administration of L-arginine has been shown to enhance production of nitric oxide (NO) and to reduce lesion formation. The goal of this study was to determine whether local intramural administration of L-arginine could enhance NO generation and reduce intimal thickening. METHODS AND RESULTS New Zealand White rabbits (n = 27) received a 1% cholesterol diet. For the short-term study, after 1 week of diet, both iliac arteries were balloon injured. Four weeks later… CONTINUE READING
BETA

Citations

Publications citing this paper.
SHOWING 1-10 OF 47 CITATIONS

Similar Papers

Loading similar papers…