Local intra‐ and interlaminar connections in mouse barrel cortex

  title={Local intra‐ and interlaminar connections in mouse barrel cortex},
  author={Kerry L. Bernardo and J. S. McCasland and Thomas A. Woolsey and Robert N. Strominger},
  journal={Journal of Comparative Neurology},
Focal injections of horseradish peroxidase (HRP) in dimethylsulfoxide (DMSO) were targeted into mouse somatosensory cortex, in vitro, with a template. Injections were made at different depths and in different locations in the whisker‐barrel‐defined somatosensory map in order to determine quantitative connectivity patterns within and between barrel‐defined cortical columns. Cortices were sectioned in a plane parallel to the pia at 75 βm. Data were collected directly from microscope slides by… 
Ipsilateral cortical connections of primary somatic sensory cortex in rats
The organization of ipsilateral cortical connections of the rat primary somatic sensory area (SI) was analyzed following small injections of multiple fluorescent tracers in the same case, into two or
Local axonal trajectories in mouse barrel cortex
The findings indicate that integration of information between whisker rows within barrel cortex involves asymmetrical connections within layer IV and infragranular layers.
Sensorimotor corticocortical projections from rat barrel cortex have an anisotropic organization that facilitates integration of inputs from whiskers in the same row
Results indicate that SI projections to MI and SII have an anisotropic organization that facilitates the integration of sensory information received from neighboring barrels that represent whiskers in the same row.
Interconnected cortical networks between primary somatosensory cortex septal columns and posterior parietal cortex in rat
It is hypothesized that septal columns may form interconnected cortical networks that engage in spatial information processing contingent on somestheic cues that may deliver vibrissal cues to PPC for spatial processing.
Somatosensory Thalamus of the Rat
This chapter concerns the thalamic nuclei that project to the barrel cortex—their classification, their afferent and efferent connections, and their functional properties.
Differential Pattern of Interhemispheric Connections Between Homotopic Layer V Regions in the Forelimb Representation in Rat Barrel Field Cortex
Results indicate that layer V neurons project to cortical laminae II–VI in contralateral SI, with the densest labeling in layer V followed by layer III, while neurons in the forepaw representation project largely to sites in perigranular and dysgranular cortex adjacent to their homotopic territory.
Functionally Independent Columns of Rat Somatosensory Barrel Cortex Revealed with Voltage-Sensitive Dye Imaging
Plasticity in the spatial extent of excitation in a barrel column could underlie changes in cortical map structure induced by alterations of sensory experience.
Corticostriatal Projections from Rat Barrel Cortex Have an Anisotropic Organization that Correlates with Vibrissal Whisking Behavior
Results indicate that corticostriatal projections from whisker barrel cortex have an anisotropic organization that correlates with the pattern of vibrissal movements during whisking behavior.
Neonatal whisker clipping alters intracortical, but not thalamocortical projections, in rat barrel cortex
It is indicated that manipulations of sensory experience alter patterns of intracortical, but not thalamic barreloid, connections, which are similar to those observed in normal rats.


Axonal trajectories between mouse somatosensory thalamus and cortex
An in vitro brain slice preparation has been used to label fibers connecting the somatosensory thalamus and cortex of the mouse with horseradish peroxidase crystals, HRP, nonidet P‐40 detergent chips, or a solution of HRP/dimethylsulfoxide.
Organization of intracortical and commissural connections in somatosensory cortical areas I and II in the raccoon
The organization of intracortical and callosal projecting cell bodies was examined in somatosensory representation areas I and II of the raccoon by use of horseradish peroxidase and HRP by using the aid of the substrates dihydrochlorobenzidine or tetramethyl benzidine in the presence of hydrogen peroxids.
High‐resolution 2‐deoxyglucose mapping of functional cortical columns in mouse barrel cortex
Cortical columns associated with barrels in layer IV of the somatosensory cortex were characterized by high‐resolution 2‐deoxy‐D‐glucose (2DG) autoradiography in freely behaving mice. The method
Corticocortical connections within the primary somatosensory cortex of the rat
The aim of this study was to determine whether the pattern of intracortical connectivity within the SI is compatible with observed physiological differences.
Acute whisker removal reduces neuronal activity in barrels of mouse sml cortex
The application of the 2‐DG method is described to assay regional activity in the posteromedial barrel subfield (PMBSF) region of the mouse SmI cortex after acute removal of mystacial vibrissae.
Computer‐assisted analyses of barrel neuron axons and their putative synaptic contacts
The “barrels” in layer IV of rodent SmI neocortex receive inputs from individual whiskers on the contralateral face and the axons of these cells were examined and the locations of close appositions to dendrites of other impregnated neurons were mapped.
Interlaminar connections of rat visual cortex: An ultrastructural study
Thermal lesions were made in layers I, II, and upper part of layer III of rat visual cortex. The distribution of degenerating axons and axon terminals in layers IV, V, and VI was studied using
Commissural and cortico-cortical "columns" in the somatic sensory cortex of primates
Anatomical experiments demonstrate that commissural and cortico-cortical fibers arising and terminating in the somatic sensor- cortex of monkeys terminate in layers I through IV in a mosaic of