Local implants of testosterone metabolites regulate vasopressin mRNA in sexually dimorphic nuclei of the rat brain.

@article{Brot1993LocalIO,
  title={Local implants of testosterone metabolites regulate vasopressin mRNA in sexually dimorphic nuclei of the rat brain.},
  author={Michelle D. Brot and G J de Vries and Daniel M. Dorsa},
  journal={Peptides},
  year={1993},
  volume={14 5},
  pages={933-40}
}
Biosynthesis of the neuropeptide vasopressin (VP) in extrahypothalamic neurons is dependent on circulating levels of testosterone (T). However, the mechanism by which endogenous or peripherally administered T induces VP gene expression in the brain has not been established. This study investigated the effects of androgens and estrogen in the steroid-dependent expression of VP mRNA in the bed nucleus of the stria terminalis (BNST). Testosterone, estrogen, and the T metabolite… CONTINUE READING

Citations

Publications citing this paper.
Showing 1-10 of 16 extracted citations

Similar Papers

Loading similar papers…