Local immunoglobulin G antibodies in the stomach may contribute to immunity against Helicobacter infection in mice.

@article{Ferrero1997LocalIG,
  title={Local immunoglobulin G antibodies in the stomach may contribute to immunity against Helicobacter infection in mice.},
  author={Richard L Ferrero and Jean Michel Thiberge and Agn{\'e}s Labigne},
  journal={Gastroenterology},
  year={1997},
  volume={113 1},
  pages={185-94}
}
BACKGROUND & AIMS Orogastric immunization of mice with Helicobacter antigens, together with a mucosal adjuvant (cholera toxin), has been shown to confer immunity in the Helicobacter felis infection model. The aim of the study was to investigate the humoral immune responses associated with immunity and to compare these with responses in H. felis-infected mice. METHODS Enzyme-linked immunoassays were used to characterize the antibody-secreting cells and antibodies present at mucosal and… CONTINUE READING