Local hematopoietic renin-angiotensin system in myeloid versus lymphoid hematological neoplastic disorders.

@article{Uz2013LocalHR,
  title={Local hematopoietic renin-angiotensin system in myeloid versus lymphoid hematological neoplastic disorders.},
  author={Burak Uz and Suzin Catal Tatonyan and Muge Sayitoglu and Yucel Erbilgin and Ozden Hatirnaz Ng and Yahya Buyukasik and Nilgun Sayinalp and Salih Aksu and Hakan G{\"o}ker and Osman Ilhami Ozcebe and Uğur Ozbek and İbrahim Celalettin Haznedaroğlu},
  journal={Journal of the renin-angiotensin-aldosterone system : JRAAS},
  year={2013},
  volume={14 4},
  pages={
          308-14
        }
}
There is preliminary evidence that the local renin-angiotensin system (RAS) could affect neoplastic hematopoiesis. The aim of this study is to search messenger RNA (mRNA) expressions of the essential RAS elements in myeloid and lymphoid hematological neoplastic disorders. Forty-six patients with newly diagnosed myeloid (AML, biphenotypic leukemia, CML) or lymphoid (CLL, NHL, B-ALL, T-ALL) hematological disorders were included in the study. In the lymphoid group, the median expression values of… CONTINUE READING
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