Local folding and misfolding in the PBX homeodomain from a three-state analysis of CPMG relaxation dispersion NMR data.

Abstract

NMR Carr-Purcell-Meiboom-Gill (CPMG) relaxation dispersion experiments represent a powerful approach for characterizing protein internal motions and for gaining insight into fundamental biological processes such as protein folding, catalysis, and allostery. In most cases, CPMG data are analyzed assuming that the protein exchanges between two different… (More)
DOI: 10.1021/jp306127m

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