Local dynamics of gap-junction-coupled interneuron networks.

  title={Local dynamics of gap-junction-coupled interneuron networks.},
  author={Troy Matthew Lau and Gregory J. Gage and Joshua D. Berke and Michal Zochowski},
  journal={Physical biology},
Interneurons coupled by both electrical gap-junctions (GJs) and chemical GABAergic synapses are major components of forebrain networks. However, their contributions to the generation of specific activity patterns, and their overall contributions to network function, remain poorly understood. Here we demonstrate, using computational methods, that the topological properties of interneuron networks can elicit a wide range of activity dynamics, and either prevent or permit local pattern formation… CONTINUE READING
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