Local control of neurite sprouting in cultured sympathetic neurons by nerve growth factor.

@article{Campenot1987LocalCO,
  title={Local control of neurite sprouting in cultured sympathetic neurons by nerve growth factor.},
  author={Robert B. Campenot},
  journal={Brain research},
  year={1987},
  volume={465 1-2},
  pages={293-301}
}
Sprouting of neurites by sympathetic neurons from newborn rats was studied in compartmentalized cultures. The neuronal cell bodies resided in proximal compartments, and neurites penetrated silicone grease barriers and elongated within distal compartments. Nerve growth factor (NGF) was initially supplied at 1 microgram/ml in all compartments, but was subsequently withdrawn from proximal compartments and for a time was only supplied to distal neurites. Little or no neurite growth was observed in… CONTINUE READING
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