• Corpus ID: 237266862

Local contact inhibition leads to universal principles of cell population growth

  title={Local contact inhibition leads to universal principles of cell population growth},
  author={Gregory J. Kimmel and Jeffrey West and Mehdi Damaghi and Alexander R. A. Anderson and Philipp M. Altrock},
Cancer cell population dynamics often exhibit remarkably replicable, universal laws despite their underlying heterogeneity. Mechanistic explanations of universal cell population growth remain partly unresolved to this day, whereby population feedback between the microscopic and mesoscopic configurations can lead to macroscopic growth laws. We here present a unification under density-dependent birth events via contact inhibition. We consider five classical tumor growth laws: exponential… 
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