Local cell membrane deformations due to receptor-ligand bonding as seen by reflection microscopy.

@article{Galle2002LocalCM,
  title={Local cell membrane deformations due to receptor-ligand bonding as seen by reflection microscopy.},
  author={Joerg Galle and Ina Reibiger and Martin Westermann and Wolfgang Richter and Stefan L{\"o}ffler},
  journal={Cell communication & adhesion},
  year={2002},
  volume={9 3},
  pages={161-72}
}
Understanding surface receptor clustering and redistribution processes at the cell-matrix contact zone requires detailed knowledge of the spatial integration of these molecules in the architecture of this complex interface. Here we present and discuss critically a procedure to extract such information combining reflection contrast microscopy (RCM) and reflection interference microscopy (RIM). As model system, we used living human umbilical vein endothelial cells (HUVEC) adhering to laminin… CONTINUE READING

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