Local burn injury impairs epithelial permeability and antimicrobial peptide barrier function in distal unburned skin.

@article{Plichta2014LocalBI,
  title={Local burn injury impairs epithelial permeability and antimicrobial peptide barrier function in distal unburned skin.},
  author={Jennifer K. Plichta and Steve Droho and Brenda J Curtis and Parita Patel and Richard L. Gamelli and Katherine A. Radek},
  journal={Critical care medicine},
  year={2014},
  volume={42 6},
  pages={e420-31}
}
OBJECTIVES Our objective was to characterize the mechanisms by which local burn injury compromises epithelial barrier function in burn margin, containing the elements necessary for healing of the burn site, and in distal unburned skin, which serves as potential donor tissue. DESIGN Experimental mouse scald burn injury. SETTING University Research Laboratory. SUBJECTS C57/Bl6 Male mice, 8-12 weeks old. INTERVENTIONS To confirm that dehydration was not contributing to our observed barrier… CONTINUE READING

From This Paper

Figures, tables, results, connections, and topics extracted from this paper.