Local applications but global implications: Can pesticides drive microorganisms to develop antimicrobial resistance?

@article{Ramakrishnan2019LocalAB,
  title={Local applications but global implications: Can pesticides drive microorganisms to develop antimicrobial resistance?},
  author={Balasubramanian Ramakrishnan and Kadiyala Venkateswarlu and Nambrattil Sethunathan and Mallavarapu Megharaj},
  journal={The Science of the total environment},
  year={2019},
  volume={654},
  pages={
          177-189
        }
}

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References

SHOWING 1-10 OF 201 REFERENCES

Novel Antibiotic Resistance Determinants from Agricultural Soil Exposed to Antibiotics Widely Used in Human Medicine and Animal Farming

The discovery of several previously unknown antibiotic resistance genes from uncultured soil microorganisms indicates that soil is a significant reservoir of resistance determinants, which, once acquired and “repurposed” by pathogenic bacteria, can have serious impacts on therapeutic outcomes.

The Rising Tide of Antimicrobial Resistance in Aquaculture: Sources, Sinks and Solutions

As the human population increases there is an increasing reliance on aquaculture to supply a safe, reliable, and economic supply of food, and it is essential that the sources and sinks of antimicrobial resistance are identified and monitored, in order to better understand the implications to human and environmental health.

Bacterial biodegradation of neonicotinoid pesticides in soil and water systems.

This review focuses on the biodegradation of neonicotinoid-mineralising bacterial strains in soil and water systems by the bacterial community and indicates that enhanced biotransformation of these pesticides can be accomplished by mixed microbial populations under optimised environmental conditions.

Bacterial Chemotaxis toward Environmental Pollutants: Role in Bioremediation

Recent discoveries in bacterial chemotaxis toward pollutants are described and how they may be explored and exploited for bioremediation applications are described.

Bloom of resident antibiotic-resistant bacteria in soil following manure fertilization

It is found that dairy cow manure amendment enhanced the proliferation of resident antibiotic-resistant bacteria and genes encoding β-lactamases in soil even though the cows from which the manure was derived had not been treated with antibiotics.

The evolution of new enzyme function: lessons from xenobiotic metabolizing bacteria versus insecticide-resistant insects

The evolutionary routes by which bacteria and insects have evolved enzymatic processes for the degradation of four classes of synthetic chemical insecticide support recent theory proposing that new biochemical functions often evolve from ‘promiscuous' activities in existing enzymes, with subsequent mutations then enhancing those activities.

Fertilizing with Animal Manure Disseminates Antibiotic Resistance Genes to the Farm Environment.

This study shows that antibiotic resistance genes are disseminated on Finnish production animal farms, and the spreading of resistance genes in farm-associated environments could possibly be limited by experimenting with new manure handling methods that could reduce the abundance of the genes in manure used for land application.

Antibiotics in Agroecosystems: Introduction to the Special Section.

This introduction summarizes the current state of science for analyzing antibiotics and antibiotic resistance in agroecosystems, discusses current knowledge gaps, and develops future research priorities.
...