Local antibiotics to prevent surgical site infections: another Zeno's paradox?


A S REPORTED IN JAMA, THE SWIPE-1 TRIAL used the implantation of 2 gentamicincollagen sponges between the sternal halves in an effort to prevent sternal wound infections after cardiac surgery. The trial was based on an earlier large trial (2000 patients at 2 sites) that demonstrated a benefit to the sponge application. SWIPE-1 was a phase 3, single-blind… (More)
DOI: 10.1001/archsurg.2011.21


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