Local and systemic hemorheological effects of cerebral hyper- and hypoperfusion in a porcine model.

@article{Nmeth2006LocalAS,
  title={Local and systemic hemorheological effects of cerebral hyper- and hypoperfusion in a porcine model.},
  author={Norbert N{\'e}meth and Jens Soukup and Matthias Menzel and Dirk Henze and Tobias Clausen and Andreas Rieger and Carsten A. Holz and Alexander Scharf and Frank Hanisch and Istv{\'a}n Furka and Ir{\'e}n Mik{\'o}},
  journal={Clinical hemorheology and microcirculation},
  year={2006},
  volume={35 1-2},
  pages={59-65}
}
Using a well defined pig model, we investigated whether cerebral hypertension and hypotension influence hemorheological factors. After surgical preparation and stabilization, periods of hyperventilation, controlled periods of cerebral perfusion pressure increases and decreases were utilized. After each period, blood samples were collected from the cannulated femoral artery and vein, and from the superior sagittal sinus. Erythrocyte deformability, whole blood and plasma viscosity and… CONTINUE READING