Local and systemic consequences of acute, low-dose ultraviolet B radiation are mediated by different immune regulatory mechanisms.

@article{Shimizu1994LocalAS,
  title={Local and systemic consequences of acute, low-dose ultraviolet B radiation are mediated by different immune regulatory mechanisms.},
  author={Toshiki Shimizu and J. Wayne Streilein},
  journal={European journal of immunology},
  year={1994},
  volume={24 8},
  pages={1765-70}
}
Acute, low-dose ultraviolet B (UVB) radiation alters the local skin site such that epicutaneous application of hapten fails to induce contact hypersensitivity (CH), but induces tolerance in UVB-susceptible mice. Although the inability of irradiated skin to support CH induction may be a strictly local effect, there may also be systemic immune consequences of… CONTINUE READING