Local and cis Effects of the H Element on Expression of Odorant Receptor Genes in Mouse

Abstract

From the approximately 1,200 odorant receptor (OR) genes in the mouse genome, an olfactory sensory neuron is thought to express only one gene. The mechanisms of OR gene choice are not understood. A 2.1 kilobase region (the H element) adjacent to a cluster of seven OR genes has been proposed as a trans- and pan-enhancer for OR gene expression. Here, we… (More)
DOI: 10.1016/j.cell.2007.06.023

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