Local ancestry corrects for population structure in Saccharomyces cerevisiae genome-wide association studies.

@article{Diao2012LocalAC,
  title={Local ancestry corrects for population structure in Saccharomyces cerevisiae genome-wide association studies.},
  author={Liyang Diao and Kevin Chen},
  journal={Genetics},
  year={2012},
  volume={192 4},
  pages={1503-11}
}
Genome-wide association studies (GWAS) have become an important method for mapping the genetic loci underlying complex phenotypic traits in many species. A crucial issue when performing GWAS is to control for the underlying population structure because not doing so can lead to spurious associations. Population structure is a particularly important issue in nonhuman species since it is often difficult to control for population structure during the study design phase, requiring population… CONTINUE READING

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