Local adiponectin treatment reduces atherosclerotic plaque size in rabbits.

  title={Local adiponectin treatment reduces atherosclerotic plaque size in rabbits.},
  author={C Li and Hui-wen Sun and Fa-liang Zhu and Liang Chen and Yuan-yuan Rong and Yun Zhang and Mei Zhang},
  journal={The Journal of endocrinology},
  volume={193 1},
In this study, we investigated the in vivo role of adiponectin, an adipocytokine, on the development of atherosclerosis in rabbits mainly using adenovirus expressing adiponectin gene (Ad-APN) and intravascular ultrasonography. Serum adiponectin concentrations in rabbits after Ad-APN local transfer to abdominal aortas increased about nine times as much as those before transfer (P < 0.01), about ten times as much as the levels of endogenous adiponectin in adenovirus expressing beta-galactosidase… CONTINUE READING


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Adrenomedullin overexpression to limit arterial intimal formation induced by cuff placement

  • T Yamauchi, J Kamon, +7 authors K Ueki
  • Hypertension
  • 2002
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