Local adherent technique for transplanting mesenchymal stem cells as a potential treatment of cartilage defect

  title={Local adherent technique for transplanting mesenchymal stem cells as a potential treatment of cartilage defect},
  author={H. Koga and M. Shimaya and T. Muneta and A. Nimura and T. Morito and Masaya Hayashi and S. Suzuki and Y. Ju and T. Mochizuki and I. Sekiya},
  journal={Arthritis Research \& Therapy},
  pages={R84 - R84}
IntroductionCurrent cell therapy for cartilage regeneration requires invasive procedures, periosteal coverage and scaffold use. We have developed a novel transplantation method with synovial mesenchymal stem cells (MSCs) to adhere to the cartilage defect.MethodsFor ex vivo analysis in rabbits, the cartilage defect was faced upward, filled with synovial MSC suspension, and held stationary for 2.5 to 15 minutes. The number of attached cells was examined. For in vivo analysis in rabbits, an… Expand
Effectiveness of Adhering Adipose-Derived Stem Cells to Defective Cartilage in Promoting Cartilage Regeneration in a Rabbit Model.
  • Hitoaki Numata, J. Nakase, T. Oshima, H. Tsuchiya
  • Medicine
  • Arthroscopy : the journal of arthroscopic & related surgery : official publication of the Arthroscopy Association of North America and the International Arthroscopy Association
  • 2019
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