Local White Matter Architecture Defines Functional Brain Dynamics

  title={Local White Matter Architecture Defines Functional Brain Dynamics},
  author={Sivaraman Balakrishnan and Yoonsuck Choe and Aarti Singh and Jean M. Vettel and Timothy D. Verstynen},
  journal={2018 IEEE International Conference on Systems, Man, and Cybernetics (SMC)},
Large bundles of myelinated axons, called white matter, anatomically connect disparate brain regions together and compose the structural core of the human connectome. We recently proposed a method of measuring the local integrity along the length of each white matter fascicle, termed the local connectome [1]. If communication efficiency is fundamentally constrained by the integrity along the entire length of a white matter bundle [2], then variability in the functional dynamics of brain… 

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