Local Injection of Aminoglycosides for Prophylaxis Against Infection in Open Fractures.

@article{Lawing2015LocalIO,
  title={Local Injection of Aminoglycosides for Prophylaxis Against Infection in Open Fractures.},
  author={Cheryl Reese Lawing and Feng-Chang Lin and Laurence E. Dahners},
  journal={The Journal of bone and joint surgery. American volume},
  year={2015},
  volume={97 22},
  pages={
          1844-51
        }
}
BACKGROUND The purpose of this study was to determine the efficacy of local wound cavity injections of aqueous aminoglycosides (gentamicin and tobramycin), in conjunction with systemic antibiotics, to lower the prevalence of infection in patients with open fractures. METHODS Three hundred and fifty-one open fractures were identified by Current Procedural Terminology codes 11011 and 11012. Data on patient demographic characteristics, injury characteristics, infection, and fracture union were… CONTINUE READING

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