Local Inflammatory Markers and Systemic Endotoxin in Aggressive Periodontitis

@article{Shaddox2011LocalIM,
  title={Local Inflammatory Markers and Systemic Endotoxin in Aggressive Periodontitis},
  author={Luciana M Shaddox and J Wiedey and Nadia Calder{\'o}n and Ingvar Þ{\'o}r Magn{\'u}sson and Enrique Bimstein and John Bidwell and Edward F Zapert and Ikramuddin Aukhil and Shannon M Wallet},
  journal={Journal of Dental Research},
  year={2011},
  volume={90},
  pages={1140 - 1144}
}
While much research has focused on local and systemic factors contributing to periodontal disease, little is known regarding mechanisms linking these factors. We have previously reported a systemic hyper-inflammatory response to bacterial endotoxin in localized aggressive periodontitis (LAP). The objectives of this study were to delineate cyto/chemokines in gingival crevicular fluid (GCF) and evaluate systemic levels of endotoxin associated with LAP. Clinical parameters, GCF, and peripheral… CONTINUE READING

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