Local Immunoglobulin Production in Breast Cancer

  title={Local Immunoglobulin Production in Breast Cancer},
  author={Michelle M Roberts and Eleanor M. Bass and I. W. J. Wallace and Ann Stevenson},
  journal={British Journal of Cancer},
  pages={269 - 275}
Immunoglobulin levels (IgA, IgG, IgM) have been estimated in protein extracts of 55 malignant and 20 benign tumours of the breast, and in 17 normal tissues from a cancer bearing breast. IgA and IgG were significantly reduced in cancer compared with both benign and normal tissues but IgM, detected in only a third of tumours, was significantly increased. Total immunoglobulin levels and IgG in the malignant tumours correlated with plasma cell infiltration.The menstrual status of the patient had no… CONTINUE READING