Local DNA demethylation in vertebrates: how could it be performed and targeted?

@article{Kress2001LocalDD,
  title={Local DNA demethylation in vertebrates: how could it be performed and targeted?},
  author={Cl{\'e}mence Kress and H{\'e}l{\`e}ne Thomassin and Thierry Grange},
  journal={FEBS letters},
  year={2001},
  volume={494 3},
  pages={135-40}
}
In vertebrates, cytosine methylation is an epigenetic DNA modification that participates in genome stability and gene repression. Methylation patterns are either maintained throughout cell division, or modified by global or local de novo methylation and demethylation. Site-specific demethylation is a rather elusive process that occurs mainly in parallel to gene activation during development. In light of our studies of the glucocorticoid-dependent DNA demethylation of the tyrosine… CONTINUE READING

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