Local Control of Aldosterone Production and Primary Aldosteronism.


Primary aldosteronism (PA) is caused by excessive production of aldosterone by the adrenal cortex and is determined by a benign aldosterone-producing adenoma (APA) in a significant proportion of cases. Local mechanisms, as opposed to circulatory ones, that control aldosterone production in the adrenal cortex are particularly relevant in the… (More)
DOI: 10.1016/j.tem.2016.01.003


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