Lobulocentricity of breast hypersecretory hyperplasia with cytologic atypia: infrequent association with carcinoma in situ.

@article{Kasami2004LobulocentricityOB,
  title={Lobulocentricity of breast hypersecretory hyperplasia with cytologic atypia: infrequent association with carcinoma in situ.},
  author={Masako Kasami and Roy A. Jensen and Jean F. Simpson and David L. Page},
  journal={American journal of clinical pathology},
  year={2004},
  volume={122 5},
  pages={
          714-20
        }
}
Intracytoplasmic and extracytoplasmic features of secretion, similar to lactational changes, occasionally are seen in the nonparous human breast, usually are lobulocentric, and often have aberrant cytologic and nuclear changes. In these "hypersecretory hyperplasias" (HHs; 38 women) there is bubbly cytoplasm with irregular apical cytoplasmic and/or nuclear protrusions. In a review of 138 HH cases the following additional associated changes were found: nuclear atypia (HHA, 22 women), atypical… CONTINUE READING

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[The lesions of flat epithelial atypia diagnosed on breast biopsy].

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Columnar cell lesions of the breast.

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