Lobophorins A and B, new antiinflammatory macrolides produced by a tropical marine bacterium.

@article{Jiang1999LobophorinsAA,
  title={Lobophorins A and B, new antiinflammatory macrolides produced by a tropical marine bacterium.},
  author={Zhang Jiang and Paul R Jensen and William Fenical},
  journal={Bioorganic & medicinal chemistry letters},
  year={1999},
  volume={9 14},
  pages={
          2003-6
        }
}
Two new antiinflammatory macrolides, lobophorins A and B (1 and 2), have been isolated from fermentation broths of a marine bacterium isolated from the surface the Caribbean brown alga Lobophora variegata (Dictyotales). The new compounds, distantly related to antibiotics of the kijanimicin class, are potent inhibitors of topical PMA-induced edema in the mouse ear assay when administered either topically or IP. 
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