Loading Effect on Particle Size Measurements by Inertial Sampling of Albuterol Metered Dose Inhalers

@article{Nasr1995LoadingEO,
  title={Loading Effect on Particle Size Measurements by Inertial Sampling of Albuterol Metered Dose Inhalers},
  author={Moheb M. Nasr and James F. Allgire},
  journal={Pharmaceutical Research},
  year={1995},
  volume={12},
  pages={1677-1681}
}
AbstractPurpose. The purpose of this study is to investigate the albuterol loading effect on particle size measurements by studying the effect of the amount of albuterol delivered, the number of puffs used, and the sampling techniques used in particle size measurement. Methods. Particle size distribution profiles for different albuterol loadings were evaluated using an 8-stage cascade impactor and a sensitive HPLC electrochemical assay method. A commercial albuterol MDI (ProventilR) and other… CONTINUE READING