Load-bearing increases new bone formation in impacted and morselized allografts.

@article{Wang2000LoadbearingIN,
  title={Load-bearing increases new bone formation in impacted and morselized allografts.},
  author={Janet Wang and Magnus T{\"a}gil and Per Aspenberg},
  journal={Clinical orthopaedics and related research},
  year={2000},
  volume={378},
  pages={274-81}
}
The effects of mechanical loading on the incorporation of morselized impacted grafts were addressed in this study. Twelve skeletally mature rabbits were surgically treated. Six rabbits received a proximal tibial joint replacement with a tibial tray and a load-bearing 25-mm long stem. The tibia was packed with fresh frozen, morselized, cancellous rabbit bone. No cement was used. In six other rabbits only the stem was inserted, without a tibial tray, leaving the stem and the likewise impacted… CONTINUE READING

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