Loa loa infection in temporary residents of endemic regions: recognition of a hyperresponsive syndrome with characteristic clinical manifestations.

@article{Nutman1986LoaLI,
  title={Loa loa infection in temporary residents of endemic regions: recognition of a hyperresponsive syndrome with characteristic clinical manifestations.},
  author={Thomas B Nutman and Kirk D Miller and Mark M. Mulligan and Eric A. Ottesen},
  journal={The Journal of infectious diseases},
  year={1986},
  volume={154 1},
  pages={10-8}
}
Loiasis in residents of endemic areas is generally manifested by microfilaremia, episodic angioedema, periocular migration of adult worms, modest eosinophilia, and variable antibody levels. In 20 temporary residents who acquired loiasis in West Africa, however, the clinical presentations were markedly different. Only three of the 20 had detectable microfilaremia. Furthermore, these patients often showed a state of marked immunological hyperresponsiveness manifested by very high titers of… CONTINUE READING

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