Lnk adaptor: novel negative regulator of B cell lymphopoiesis.

@article{Rudd2001LnkAN,
  title={Lnk adaptor: novel negative regulator of B cell lymphopoiesis.},
  author={Christopher E. Rudd},
  journal={Science's STKE : signal transduction knowledge environment},
  year={2001},
  volume={2001 85},
  pages={pe1}
}
Originally thought to have the functions now ascribed to the linker for activation of T cells protein (LAT), Lnk is coming into its own as an adaptor protein that mediates signaling through several receptor pathways. An essential role for Lnk in B cell development and maturation was recently uncovered by Perlmutter and colleagues. Rudd discusses the role of… CONTINUE READING