LncRNA uc.48+ is involved in the diabetic immune and inflammatory responses mediated by P2X7 receptor in RAW264.7 macrophages.

@article{Wu2018LncRNAUI,
  title={LncRNA uc.48+ is involved in the diabetic immune and inflammatory responses mediated by P2X7 receptor in RAW264.7 macrophages.},
  author={Hong Wu and Fang Wen and Mei Jiang and Qiang Liu and Yijun Nie},
  journal={International journal of molecular medicine},
  year={2018},
  volume={42 2},
  pages={1152-1160}
}
High glucose combined with high FFAs can contribute to the unfavorable development of type 2 diabetes mellitus (T2DM) and monocytes/macrophages are important in the occurrence and development of T2DM, which is regarded as a type of low‑grade inflammation. Although our previous study demonstrated that increased expression of P2X7 receptor (P2X7R) in… CONTINUE READING