LncRNA loc285194 is a p53-regulated tumor suppressor

  title={LncRNA loc285194 is a p53-regulated tumor suppressor},
  author={Qian Liu and Jianguo Huang and Nanjiang Zhou and Ziqiang Zhang and Ali Zhang and Zhaohui Lu and Fangting Wu and Yin-yuan Mo},
  booktitle={Nucleic acids research},
Protein-coding genes account for only a small part of the human genome, whereas the vast majority of transcripts make up the non-coding RNAs including long non-coding RNAs (lncRNAs). Accumulating evidence indicates that lncRNAs could play a critical role in regulation of cellular processes such as cell growth and apoptosis as well as cancer progression and metastasis. LncRNA loc285194 was previously shown to be within a tumor suppressor unit in osteosarcoma and to suppress tumor cell growth… CONTINUE READING
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