LncRNA PFL contributes to cardiac fibrosis by acting as a competing endogenous RNA of let-7d

@inproceedings{Liang2018LncRNAPC,
  title={LncRNA PFL contributes to cardiac fibrosis by acting as a competing endogenous RNA of let-7d},
  author={Haihai Liang and Zhen-Wei Pan and Xiaoguang Zhao and Li Liu and Jian Sun and Xiaomin Su and Chaoqian Xu and Yuhong Zhou and Dandan Zhao and Bozhi Xu and Xuelian Li and Baofeng Yang and Yanjie Lu and Hongli Shan},
  booktitle={Theranostics},
  year={2018}
}
Rationale: Cardiac fibrosis is associated with various cardiovascular diseases and can eventually lead to heart failure. Dysregulation of long non-coding RNAs (lncRNAs) has recently been recognized as one of the key mechanisms involved in cardiac diseases. However, the potential roles and underlying mechanisms of lncRNAs in cardiac fibrosis have not been explicitly delineated. Methods and Results: Using a combination of in vitro and in vivo studies, we identified a lncRNA NONMMUT022555, which… CONTINUE READING

References

Publications referenced by this paper.
Showing 1-10 of 45 references

Long noncoding RNA Chast promotes cardiac remodeling

Science Translational Medicine • 2016
View 4 Excerpts
Highly Influenced

MicroRNA Let-7i negatively regulates cardiac inflammation and fibrosis.

Hypertension • 2015
View 4 Excerpts
Highly Influenced

The long noncoding RNA CHRF regulates cardiac hypertrophy by targeting miR-489.

Circulation research • 2014
View 4 Excerpts
Highly Influenced

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