Liver zonation: Novel aspects of its regulation and its impact on homeostasis.

  title={Liver zonation: Novel aspects of its regulation and its impact on homeostasis.},
  author={Rolf Gebhardt and Madlen Matz-Soja},
  journal={World journal of gastroenterology},
  volume={20 26},
Liver zonation, the spatial separation of the immense spectrum of different metabolic pathways along the liver sinusoids, is fundamental for proper functioning of this organ. Recent progress in elucidating localization and interactions of different metabolic pathways by using "omics" techniques and novel approaches to couple them with refined spatial resolution and in characterizing novel master regulators of zonation by using transgenic mice has created the basis for a deeper understanding of… CONTINUE READING
Related Discussions
This paper has been referenced on Twitter 1 time. VIEW TWEETS

From This Paper

Topics from this paper.


Publications citing this paper.
Showing 1-10 of 40 extracted citations

Regulation of hepatocyte identity and quiescence

Cellular and Molecular Life Sciences • 2015
View 4 Excerpts
Highly Influenced

Glucagon contributes to liver zonation

Proceedings of the National Academy of Sciences of the United States of America • 2018

In Children With Nonalcoholic Fatty Liver Disease, Zone 1 Steatosis Is Associated With Advanced Fibrosis.

Clinical gastroenterology and hepatology : the official clinical practice journal of the American Gastroenterological Association • 2018

Similar Papers

Loading similar papers…