Liver zonation: Novel aspects of its regulation and its impact on homeostasis.

@article{Gebhardt2014LiverZN,
  title={Liver zonation: Novel aspects of its regulation and its impact on homeostasis.},
  author={Rolf Gebhardt and Madlen Matz-Soja},
  journal={World journal of gastroenterology},
  year={2014},
  volume={20 26},
  pages={8491-504}
}
Liver zonation, the spatial separation of the immense spectrum of different metabolic pathways along the liver sinusoids, is fundamental for proper functioning of this organ. Recent progress in elucidating localization and interactions of different metabolic pathways by using "omics" techniques and novel approaches to couple them with refined spatial resolution and in characterizing novel master regulators of zonation by using transgenic mice has created the basis for a deeper understanding of… CONTINUE READING
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