Liver subcellular fractions from rats treated by organosulfur compounds from Allium modulate mutagen activation.

@article{Guyonnet2000LiverSF,
  title={Liver subcellular fractions from rats treated by organosulfur compounds from Allium modulate mutagen activation.},
  author={D. Guyonnet and C. Belloir and M. Suschetet and M. Siess and A. le Bon},
  journal={Mutation research},
  year={2000},
  volume={466 1},
  pages={
          17-26
        }
}
The effects of in vivo administration of naturally occurring organosulfur compounds (OSCs) from Allium species were studied on the activation of several mutagens. Male SPF Wistar rats were given p.o. one of either diallyl sulfide (DAS), diallyl disulfide (DADS), dipropyl sulfide (DPS) or dipropyl disulfide (DPDS) during 4 consecutive days and the ability of hepatic S9 and microsomes from treated rats to activate benzo[a]pyrene (BaP), cyclophosphamide (CP), dimethylnitrosamine (DMN), N… Expand
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