Liver-specific growth factors.

  title={Liver-specific growth factors.},
  author={Wolfgang E. Fleig},
  journal={Scandinavian journal of gastroenterology. Supplement},
Experimental evidence of the existence of liver-specific growth factors has been collected for more than two decades. Blood-borne growth-promoting activity of hepatocytes may be separated into plasma and platelet-derived factors. Several groups have observed the stimulation of hepatocyte growth in vitro by some platelet-associated activity, which was recently isolated from rat platelets as a 27-kDa protein called platelet growth factor (PGF). There is evidence of at least two different growth… CONTINUE READING