Liver regeneration

@article{Fausto2006LiverR,
  title={Liver regeneration},
  author={Nelson Fausto and Jean S. Campbell and Kimberly J. Riehle},
  journal={Hepatology},
  year={2006},
  volume={43}
}
During liver regeneration after partial hepatectomy, normally quiescent hepatocytes undergo one or two rounds of replication to restore the liver mass by a process of compensatory hyperplasia. A large number of genes are involved in liver regeneration, but the essential circuitry required for the process may be categorized into three networks: cytokine, growth factor and metabolic. There is much redundancy within each network, and intricate interactions exist between them. Thus, loss of… Expand
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TLDR
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Progresses made in identifying cell types contributing to producing new hepatocytes during liver regeneration in mice and zebrafish are summarized. Expand
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An agonistic antibody against the lymphotoxin beta receptor was able to facilitate liver regeneration by reducing liver injury, increasing interleukin-6 production, hepatocyte DNA synthesis, and survival of lymphocyte-deficient (Rag) mice after partial hepatectomy. Expand
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