Liver proteome analysis in a rodent model of alcoholic steatosis.

@article{Newton2009LiverPA,
  title={Liver proteome analysis in a rodent model of alcoholic steatosis.},
  author={Billy W. Newton and William K. Russell and David H Russell and Shashi K. Ramaiah and Arul Jayaraman},
  journal={Journal of proteome research},
  year={2009},
  volume={8 4},
  pages={1663-71}
}
Alcoholic steatosis (AS) is the initial pathology associated with early stage alcoholic liver disease (ALD) and is characterized by the accumulation of fat in the liver. AS is considered clinically benign because it is reversible, and the progression of AS to alcoholic steatohepatitis (ASH) is a key step in the development of ALD. A two-dimensional gel electrophoresis (2DE)-mass spectrometry (MS) proteomic approach was used to investigate the protein expression pattern underlying AS, as the… CONTINUE READING

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