Liver iron accumulation in patients with chronic active hepatitis C: prevalence and role of hemochromatosis gene mutations and relationship with hepatic histological lesions.

@article{Hzode1999LiverIA,
  title={Liver iron accumulation in patients with chronic active hepatitis C: prevalence and role of hemochromatosis gene mutations and relationship with hepatic histological lesions.},
  author={Christophe H{\'e}zode and C{\'e}cile Cazeneuve and Olivier Cou{\'e} and Françoise Roudot-Thoraval and Isabelle Lonjon and Anne Bastie and Christophe Duvoux and Jean Michel Pawlotsky and Elie Serge Zafrani and Serge Amselem and Daniel Dhumeaux},
  journal={Journal of hepatology},
  year={1999},
  volume={31 6},
  pages={979-84}
}
BACKGROUND/AIMS Liver iron accumulation has been described in patients with chronic active hepatitis (CAH) C, and could play a role in the course of liver disease and negatively influence the response to interferon. The aim of this study was to determine the prevalence and severity of liver iron accumulation in CAH C, to assess its relationship with the HFE C282Y and H63D mutations, and to study its interactions with hepatic histological lesions. METHODS Two hundred and nine patients (131 men… CONTINUE READING
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