Liver-intestine cadherin: molecular cloning and characterization of a novel Ca(2+)-dependent cell adhesion molecule expressed in liver and intestine

@article{Berndorff1994LiverintestineCM,
  title={Liver-intestine cadherin: molecular cloning and characterization of a novel Ca(2+)-dependent cell adhesion molecule expressed in liver and intestine},
  author={Dietmar Berndorff and Reinhard Gessner and Bertolt Kreft and Norbert Schnoy and A. M. Lajous-Petter and N Loch and Werner Reutter and Michael Hortsch and Rudolf Tauber},
  journal={The Journal of Cell Biology},
  year={1994},
  volume={125},
  pages={1353 - 1369}
}
A novel member of the cadherin family of cell adhesion molecules has been characterized by cloning from rat liver, sequencing of the corresponding cDNA, and functional analysis after heterologous expression in nonadhesive S2 cells. cDNA clones were isolated using a polyclonal antibody inhibiting Ca(2+)-dependent intercellular adhesion of hepatoma cells. As inferred from the deduced amino acid sequence, the novel molecule has homologies with E-, P-, and N-cadherins, but differs from these… CONTINUE READING

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