Liver integrity after warm ischemia in situ and brief preservation ex vivo: the value of aerobic post-conditioning.

@article{Manekeller2007LiverIA,
  title={Liver integrity after warm ischemia in situ and brief preservation ex vivo: the value of aerobic post-conditioning.},
  author={Steffen Manekeller and Viola Dobberahn and Andreas Hirner and Thomas Minor},
  journal={Cryobiology},
  year={2007},
  volume={55 3},
  pages={
          249-54
        }
}
We evaluated the respective effects of warm ischemic injury in non-heart-beating donor (NHBD) grafts and/or cold ischemia time on liver viability. Eventually, the restorative potential of oxygenated hypothermic perfusion after cold storage should be investigated. Livers were retrieved from male Wistar rats and preserved with HTK-solution for 6h or 18 h by cold storage (CS). Organ retrieval took place either prior to (ctrl.) or 30 min after cardiac arrest (NHBD). Compared to 6h CS of ctrl… CONTINUE READING
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