Liver injury induced by paracetamol and challenges associated with intentional and unintentional use

  title={Liver injury induced by paracetamol and challenges associated with intentional and unintentional use},
  author={Laura Rotundo and Nikolaos T. Pyrsopoulos},
  journal={World Journal of Hepatology},
  pages={125 - 136}
Drug induced liver injury (DILI) is a common cause of acute liver injury. Paracetamol, also known as acetaminophen, is a widely used anti-pyretic that has long been established to cause liver toxicity once above therapeutic levels. Hepatotoxicity from paracetamol overdose, whether intentional or non-intentional, is the most common cause of DILI in the United States and remains a global issue. Given the increased prevalence of combination medications in the form of pain relievers and… 

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