Liver inflammation and cancer: The role of tissue microenvironment in generating the tumor-promoting niche (TPN) in the development of hepatocellular carcinoma.

@article{Galun2016LiverIA,
  title={Liver inflammation and cancer: The role of tissue microenvironment in generating the tumor-promoting niche (TPN) in the development of hepatocellular carcinoma.},
  author={Eithan Galun},
  journal={Hepatology},
  year={2016},
  volume={63 2},
  pages={354-6}
}
H epatocellular cancer (HCC) has become a leading cause of cancer-related deaths. This is apparent despite both intensive efforts, including anti-hepatitis B virus vaccination implementation worldwide and the introduction of anti-hepatitis C virus drugs that have proved to be very effective. Despite these medical advances, the prevalence of chronic liver inflammation, a main risk factor for the development of HCC, is increasing. This is related to the world-wide “epidemic” of metabolic syndrome… CONTINUE READING
Related Discussions
This paper has been referenced on Twitter 3 times. VIEW TWEETS

References

Publications referenced by this paper.
Showing 1-10 of 12 references

Lineage fate of ductular reactions in liver injury and carcinogenesis

S J€ors, P Jeliazkova, +3 authors J Ferrer
J Clin Invest 2015;125:2445-2457 • 2015

Signaling by IL-6 promotes alternative activation of macrophages to limit endotoxemia and obesity-associated resistance to insulin

J Mauer, B Chaurasia, +3 authors KD Nguyen
Nat Immunol • 2014

Similar Papers

Loading similar papers…