[Liver infarcts with early HELLP syndrome and probable catastrophic antiphospholipid syndrome].

Abstract

INTRODUCTION Among microangiopathic disorders of pregnancy, catastrophic antiphospholipid syndrome (CAPS) is a maternal and fetal life-threatening disorder. Hepatic involvement of this multi-systemic disorder can be confused with HELLP syndrome, occurring usually later in the course of pregnancy. CASE REPORT We report a case of probable CAPS with hepatic disease in a pregnant woman at 13 week's gestation, with antiphospholipid syndrome and biological features of HELLP syndrome. Unspecific hepatic imaging, well-described in our case allowed undelayed therapy. CONCLUSION CAPS and HELLP syndrome, both severe microangiopathic disorders, may be associated. Nosological distinction does not modify treatment strategy, which is a maternal and foetal emergency, but their overlapping requires aggressive and early management.

DOI: 10.1016/j.revmed.2008.09.013

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Cite this paper

@article{dYthurbide2009LiverIW, title={[Liver infarcts with early HELLP syndrome and probable catastrophic antiphospholipid syndrome].}, author={G{\'e}raldine d'Ythurbide and Pascal Rousset and B. Carbonne and Jean Cabane and Laurence Fardet and K P Tiev and Adrien Kettaneh}, journal={La Revue de medecine interne}, year={2009}, volume={30 3}, pages={255-9} }