Liver function and splanchnic ischemia in critically ill patients.

  title={Liver function and splanchnic ischemia in critically ill patients.},
  author={Nicholas D. Maynard and David J Bihari and Rosemary Dalton and Richard Beale and Mark Smithies and Robert C. Mason},
  volume={111 1},
STUDY OBJECTIVE To investigate the concept that splanchnic ischemia leads to hepatic dysfunction in the critically ill. DESIGN Prospective study and analysis of patient data. SETTING A general ICU in an inner-city London teaching hospital. PATIENTS Twenty-seven consecutive critically ill patients with evidence of inadequate tissue perfusion requiring pulmonary artery catheterization and mechanical ventilation. MEASUREMENTS In all patients, we measured the hepatic metabolism of lidocaine… CONTINUE READING


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